{"id":18337,"date":"2024-02-07T13:09:23","date_gmt":"2024-02-07T06:09:23","guid":{"rendered":"https:\/\/www.dent.nu.ac.th\/?page_id=18337"},"modified":"2024-05-17T13:45:25","modified_gmt":"2024-05-17T06:45:25","slug":"%e0%b8%ad-%e0%b8%97%e0%b8%9e%e0%b8%8d-%e0%b8%94%e0%b8%a3-%e0%b8%97%e0%b8%b1%e0%b8%a8%e0%b8%99%e0%b9%8c%e0%b8%97%e0%b8%a7%e0%b8%b5-%e0%b9%80%e0%b8%82%e0%b9%87%e0%b8%a1%e0%b8%a7%e0%b8%87%e0%b8%a9","status":"publish","type":"page","link":"https:\/\/www.dent.nu.ac.th\/?page_id=18337","title":{"rendered":"\u0e1c\u0e28.\u0e14\u0e23.\u0e17\u0e1e\u0e0d.\u0e17\u0e31\u0e28\u0e19\u0e4c\u0e17\u0e27\u0e35 \u0e40\u0e02\u0e47\u0e21\u0e27\u0e07\u0e29\u0e4c"},"content":{"rendered":"
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\n\t\n\t\tThe Department of Oral Diagnosis (The Oral Medicine Division)\t<\/a>\n<\/div>\n
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Ruchadaporn Kaomongkolgit, DDS, MSc, PhD<\/strong>
Contact: ruchadapornk@nu.ac.th
Research interests: Oral mucosal diseases, Oral candidiasis, Oral cancer, Natural products<\/h5>\n<\/div>
Description of current research<\/strong><\/h5>\n
My current research is focusing on the oral mucosal diseases and gerodontology. The main interest is in the demographic and clinical profile of these diseases, moreover, trying to find new agents from natural products for use as alternative treatment of oral fungal infection, bacterial infection and oral cancer.
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\nPublications<\/strong><\/p>\n

1. Daroonpan P, Ouchi R, Zhang C, Nagai S, Nishii N, Kashima Y, et. al. Personal immune profiles: Diversity and prognostic value for oral tongue squamous cell carcinoma evaluated by comprehensive immune parameter analyses with multiplex immunofluorescence. Oral Oncol. 2023 Aug;143:106458.
2. Kaomongkolgit R. Amlodipine-induced gingival overgrowth in older patients: a report of four cases. Asian Journal of Gerontology and Geriatrics. 2023; 18(1): 36-38.
3. Yiemwattana I, Kaomongkolgit R, Wirojchanasak S, Nathamtong S, Wacharanad S. Inhibitory effect of Morus alba stem extract on bacterial biofilms and matrix metalloproteinase (MMP)-1, and MMP-2 expression in vitro. Journal of International Dental and Medical Research. 2023; 16(1): 1-7.
4. Chompunud Na Ayudhya C, Kaomongkolgit R. Malignant transformation of oral lichen planus during COVID-19 crisis. Oral Diseases. 2022 Nov 2:10.1111\/odi.14423.
5. Kaomongkolgit R, Sawangarun W. Oral lichen planus following mRNA COVID-19 vaccination. Oral Diseases. 2022; 28 Suppl 2: 2622-2623.
6. Kaomongkolgit R, Tantanapornkul W, Palasuk J, Yiemwattana I, Boontiengtrong A. Herpetiform recurrent aphthous stomatitis associated with iron deficiency anemia in a child. Pediatric Nursing. 2022; 48(2): 94-96.
7. Kaomongkolgit R, Sarideechaigul W, Klanrit P, Phothipakdee P. Clinical profile of oral pemphigus vulgaris in Thai patients. Family Medicine & Primary Care Review. 2021; 23(4): 442\u2013446.
8. Tantanapornkul W, Kaomongkolgit R, Tohnak S, Deepho C, Chansamat R. Chronological age assessment based on the root pulp visibility in lower third molars in a group of Thai population: panoramic radiographic study. Open Dentistry Journal. 2021; 15: 591-594.
9. Tantanapornkul W, Kaomongkolgit R, Tohnak S, Deepho C, Chansamat R. Dental age assessment based on the radiographic visibility of the periodontal ligament in lower third molars in a Thai sample. Journal of Forensic Odontostomatology. 2021; 39(2): 32-37.
10. Kaomongkolgit R. Allergic contact stomatitis associated with traditional medicine in an elderly female patient. Journal of Pakistan Association of Dermatologists. 2021; 31(2): 308-311.
11. Deepho J, Tohnak S, Kaomongkolgit R, Chansamat R, Tantanapornkul W, The infraorbital ethmoid (Haller\u2019s) cells in a group of Thai patients: Panoramic radiographic study. Journal of International Dental and Medical Research. 2020; 13(2): 566-570.
12. Daroonpan P, Kaomongkolgit R, Tantanapornkul W, Palasuk J. Demographic and clinical profile of gingival oral lichen planus in a group of Thai individuals. Journal of Dentistry Indonesia. 2020; 27(1): 33-37.
13. Tantanapornkul W, Kaomongkolgit R, Tohnak S, Promma L, Chantarangsu S. Erupted compound odontoma associated with missing tooth: A rare case report. Journal of Dentistry Indonesia. 2020; 27(1): 46-49.
14. Kaomongkolgit R, Daroonpan P, Tantanapornkul W, Palasuk J. Clinical profile of 102 patients with oral lichen planus in Thailand. Journal of Clinical and Experimental Dentistry. 2019; 11(7): e625-e629.
15. Kaomongkolgit R, Tantanapornkul W. Rare case of etoricoxib-induced oral ulceration. Journal of International Dental and Medical Research. 2019; 12(3): 1174-1176.
16. Yiemwattana I, Kaomongkolgit R, Wirojchanasak S, Chaisomboon N. Morus alba stem extract suppresses matrix metalloproteinases (MMP)-1, MMP-9, and tissue inhibitors of metalloproteinase (TIMP)-1 expression via inhibition of I\u03baB\u03b1 degradation induced by Porphyromonas gingivalis LPS signal in THP-1 cells. European Journal of Dentistry. 2019; 13(2): 229-234.
17. Kaomongkolgit R, Daroonpan P, Tantanapornkul W, Palasuk J, Chansamat R. Medical conditions and oral diseases in elderly Thai dental patients in lower northern Thailand. Journal of Dentistry Indonesia. 2019; 26(3): 153-159.
18. Samprasit W, Akkaramongkolporn P, Kaomongkolgit R, Opanasopit P. Cyclodextrin-based oral dissolving films formulation of taste-masked meloxicam. Journal Pharmaceutical Development and Technology. 2018; 23(5): 530-539.
19. Wongviriya A, Samnieng P, Intapa C, Phothipakdee P, Kaomongkolgit R. Oral mucosal lesions in Thai elderly dental patients. Journal of the Medical Association of Thailand. 2018; 101(3): 367-373.
20. Kaomongkolgit R, Jamdee K. Inhibitory effect of alpha-mangostin on candida biofilms. Odontology. 2017; 105(2): 248-253.
21. Kaomongkolgit R, Tantanapornkul W. Chronological age estimation base on third molar development from panoramic radiograph in Thai population. Journal of International Dental and Medical Research. 2017; 10(1): 65-71
22. Kaomongkolgit R, Wongviriya A, Daroonpan P, Chansamat R, Tantanapornkul W, Palasuk J. Denture stomatitis and its predisposing factors in denture wearers. Journal of International Dental and Medical Research. 2017; 10(1): 89-94.
23. Kaomongkolgit R, Tantanapornkul W, Lekatana H. Inflammatory papillary hyperplasia of gingiva as a manufestation of allergic contact stomatitis caused by amalgam core preparation. Journal of International Dental and Medical Research. 2017; 10(1): 166-168.
24. Kaomongkolgit R, Tantanapornkul W. Pattern of impacted third molar in Thai population: retrospective radiographic survey. Journal of International Dental and Medical Research. 2017 ;10(1): 30-35.
25. Patrojanasophon P, Rojanarata T, Ngawhirunpat T, Akkaramongkolporn P, Kaomongkolgit R, Opanasopit P. Erythrosine incorporated fast-dissolving patches for dental plaque disclosing. Advances in Pharmacology and Pharmacy. 2017; 5(1): 12-19.
26. Kaomongkolgit R, Yiemwattana I. Alpha-mangostin suppresses 12-o-tetradecanoylphorbol -13-acetate-mediated matrix metalloproteinase-9 expression in human osteosarcoma cells U2OS. Tropical Journal of Pharmaceutical Research. 2016; 15(10): 2063-2070.
27. Yiemwattana I, Kaomongkolgit R. Porphyromonas gingivalis LPS-induced IL-1\u03b2 and IL-8 Expression by Reducing MAPK Activation in THP-1 Cells. West Indian Medical Journal. 2016.
28. Patrojanasophon P, Ngawhirunpat T, Rojanarata T, Kaomongkolgit R, Opanasopit P. Fabrication and evaluation of nanostructured herbal oil\/hydroxypropyl-\u03b2 cyclodextrin \/polyvinylpyrrolidone mats for denture stomatitis prevention and treatment. American Association of Pharmaceutical Scientists. 2016; 17(6): 1441-1449.
29. Kaomongkolgit R, Jamdee, K. Inhibitory effect of alpha-mangostin on adhesion of candida albicans to denture acrylic. Open Dentistry Journal. 2015; 9: 388-392.
30. Kaomongkolgit R, Subbalekha K, Sawangarun W, Thongprasom K. Pyoderma gangrenosum-like oral ulcerations in an elderly patient. Gerodontology. 2015; 32(4): 309-313.
31. Patrojanasophon P, Ngawhirunpat T, Rojanarata T, Panomsuk S, Kaomongkolgit R, Opanasopit P. Fabrication of mucoadhesive chitosan coated polyvinylpyrrolidone\/cyclodextrin\/ clotrimazole sandwich patches for oral candidiasis. Carbohydrate Polymers. 2015; 132: 173-179.
32. Yiemwattana I, Kaomongkolgit R. Alpha-mangostin suppresses IL-6 and IL-8 expression in p. gingivalis lps-stimulated human gingival fibroblasts. Odontology. 2015; 103(3): 348-355.
33. Kaomongkolgit R, Tantanapornkul W, Jittapiromsak N, Ngamwannagul P, Sriaroon P. Severe anti-epileptic drug-induced gingival overgrowth in a physically disabled patient. West Indian Medical Journal. 2015; 65(1); 212-215.
34. Samprasit W, Akkaramongkolporn P, Ngawhirunpat T, Rojanarata T, Kaomongkolgit R, Opanasopit P. Fast releasing oral electrospun pvp\/cd nanofiber mats of taste-masked meloxicam. International Journal of Pharmaceutics. 2015; 487(1-2): 213-222.
35. Samprasit W, Kaomongkolgit R, Sukma M, Rojanarata T, Ngawhirunpat T, Opanasopit P. Mucoadhesive electrospun chitosan-based nanofibre mats for dental caries prevention. Carbohydrate Polymers. 2015; 117: 933-940.
36. Samprasit W, Rojanarata T, Akkaramongkolporn P, Ngawhirunpat T, Kaomongkolgit R, Opanasopit P. Fabrication and in vitro\/in vivo performance of mucoadhesive electrospun nanofiber mats containing \u03b1-mangostin. American Association of Pharmaceutical Scientists. 2015; 16(5): 1140-1152.
37. Patrojanasophon P, Ngawhirunpat T, Rojanarata T, Kaomongkolgit R, Opanasopit P. Fabrication of a novel scaffold of clotrimazole-microemulsion-containing nanofibers an electrospinning process for oral candidiasis applications. Colloids and surfaces B: biointerface. 2015; 126: 18-25.
38. Samprasit W, Opanasopit P, Sukma M, Kaomongkolgit R. Antibacterial activity of Garcinia mangostana extracts on oral pathogens. Minerva Stomatologica. 2014; 63(7-8): 249-257.
39. Patrojanasophon P, Ngawhirunpat T, Rojanarata T, Kaomongkolgit R, Opanasopit P. Fast-acting clotrimazole composited PVP\/HP\u03b2CD nanofibers for oral candidiasis application. Pharmaceutical Research. 2014; 31(8): 1893-1906.
40. Patrojanasophon P, Ngawhirunpat T, Rojanarata T, Kaomongkolgit R, Opanasopit P Fabrication and evaluation of clotrimazole-loaded PVP\/HP\u03b2CD nanofiber mats for oral candidiasis. Thai Journal of Pharmaceutical Sciences. 2013; 38: 255-259.
41. Kaomongkolgit R. Alpha-mangostin suppresses MMP-2 and MMP-9 expression in head and neck squamous carcinoma cells. Odontology. 2013; 101(2): 227-232.
42. Kaomongkolgit R, Jamdee K, Pumklin J, Pavasant P. Laboratory evaluation of the antibacterial and cytotoxic effect of alpha-mangostin when used as a root canal irrigant. Indian Journal of Dentistry. 2013; 4: 12-17.
43. Kaomongkolgit R, Jamdee K, Wongnoi S, Chimnoi N, Techasakul S. Antifungal activity of coronarin D against Candida albicans. Oral Surgery Oral Medicine Oral Pathology Oral Radiology. 2012; 114(1): 61-66.
44. Kaomongkolgit R, Chaisomboon N, Pavasant P. Apoptotic effect of alpha-mangostin on head and neck squamous carcinoma cells. Archives of Oral Biology. 2011; 56(5): 483-490.
45. Kaomongkolgit R. Oral lichenoid drug reaction associated with antihypertensive and hypoglycemic drugs. Journal of drugs in dermatology. 2010; 9(1): 73-75.
46. Kaomongkolgit R, Manokawinchoke J, Sanchavanakit N, Pavasant P, Sumrejkanchanakij P. Fibronectin supports TNF-alpha-induced osteopontin expression through beta1 integrin and ERK in HN-22 cells. Archives of Oral Biology. 2010; 55(2): 101-107.
47. Kaomongkolgit R, Jamdee K, Chaisomboon N. Antifungal activity of alpha-mangostin against Candida albicans. Journal of Oral Science. 2009; 51(3): 401-406.
48. Kaomongkolgit R, Cheepsunthorn P, Pavasant P, Sanchavanakit N. Iron increases MMP-9 expression through activation of AP-1 via ERK\/Akt pathway in human head and neck squamous carcinoma cells. Oral Oncology. 2008; 44(6): 587-594.
49. Sanchavanakit N, Sangrungraungroj W, Kaomongkolgit R, Banaprasert T, Pavasant P, Phisalaphong M. Growth of human keratinocytes and fibroblasts on bacterial cellulose film. Biotechnology Progress. 2006; 22(4): 1194-1199.<\/p>\n<\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/section>

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\n\t\n\t\tThe Department of Oral Diagnosis (Division of Oral Medicine)\t<\/a>\n<\/div>\n
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Thatawee Khemwong, D.D.S., Ph.D.<\/strong>
Contact:<\/strong> thataweek@nu.ac.th
Research interest:<\/strong> Immunology of periodontology, Oral micro-organism, Periodontal diseases, Denture stomatitis, Oral Inflammation and infections<\/h5>\n<\/div>
Description of current research<\/strong><\/h5>\n
My research primarily focuses on the etiopathogenesis of periodontitis. I am investigating the connections between periodontopathogens, immunity, and systemic conditions such as diabetes mellitus and preterm birth. Studies indicate a higher likelihood of periodontal diseases in individuals with diabetes. There is also evidence suggesting a correlation between periodontopathogenic bacteria and preterm birth. Additionally, I am interested in determining the risk of periodontitis in large populations by identifying oral bacteria and biomarkers from saliva. This comprehensive approach offers a deep understanding of periodontitis from various perspectives, providing valuable insights for the prevention, diagnosis, and treatment of periodontal disease.
Furthermore, my research extends to oral mucosal diseases, aiming to evaluate the connections among oral microbiota, mucosal immunity, and oral epithelium with the goal of developing novel therapeutic approaches for managing oral mucosal diseases.<\/h5>\n<\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/section>
4-1-2 OM TK<\/a><\/div><\/div><\/div><\/div><\/div><\/section>
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